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Trump's weight loss drug announcement raises questions from the commercial market to Medicare.

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for glycaemic control in patients with type 2 diabetes, have demonstrated significant cardiometabolic benefits

Peak GLP-1 increases were significantly higher (~32%) after RYGB at both follow-ups (p<0.05)

Semaglutide works in a similar way by helping to slow down how quickly food leaves the stomach and by acting on areas of the brain involved in appetite control