glp-1/gip/glucagon triple agonist Retatrutide: The Triple-Agonist Guide to Weight Loss, Appetite Control & Metabolic Reset What GLP‑3 Really Is: Retatrutide
Description
When you combine appetite suppression from GLP-1 activation with the insulin-sensitizing effects of GIP stimulation and the thermogenic boost from glucagon receptor engagement, you get a compounding metabolic effect that no single-receptor or dual-receptor agonist can match

They also stimulate GLP-1 secretion

143 , 5160 (2014) Wheeler, M

Contemporary classification of Glucagon-like peptide 1 receptor agonists (GLP1RAs)

Individuals with higher external eating scores at the start of the study tended to show greater weight loss
