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People with type 2 diabetes who need help with blood sugar control or who also have risk factors for cardiovascular disease are candidates for these medications, according to Diala Alatassi, MD , a double board-certified internal and obesity medicine physician at Endeavor Health in Elmhurst, IL

Not all patients respond equally to GLP-1 agonist therapy, and identifying optimal candidates requires considering multiple factors, including baseline weight, comorbidities, and individual tolerance profiles

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Interestingly, in a study published in 2024, researchers examined the dynamic, wide-ranging molecular environment in the intact human ileum and found that when plant-based foods with intact cellular structures are consumed, they can increase the delivery of nutrients to the ileum, which subsequently can lead to an increased release of satiety peptides (in particular, PYY)