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2 Moreover, PCOS may present as an irregular cycle, defined by an abnormal duration of 35 days or several cycles 35 days), the bleeding ratio, which is the number of menstrual bleedings divided by the study period in months that can aid in the detection of menstrual irregularities and the impact of treatment, increased in 62% of patients suffering from PCOS in the liraglutide (1.8 mg/day) intervention group in comparison to placebo at 28% 81 (Figure 3(b))

FIGURE 7 The study was repeated using the same rat model to compare responses to 10, 25 and 50 g semaglutide applied to the intestinal surface versus 10-fold lower doses applied via the i.v