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Intriguingly, in our study, we observed that TIR treatment prevented the HG induced mRNA and protein downregulation of GLUT3 along with GLUT1, GLUT4, and SORBS1, a protein that takes part in diabetes pathogenesis [31], and regulates GLUT4 translocation [32] affecting neuronal insulin resistance [63]

GS-0976 reduces hepatic steatosis and fibrosis markers in patients with nonalcoholic fatty liver disease

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73 Rinella ME, Noureddin M
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The interplay of glucagon-like peptide-1 receptor trafficking and signalling in pancreatic beta cells
