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(2024) synthesized clinical and observational data regarding the effects of GLP-1RAs on alcohol use

485,486 This affects the synthesis of triacylglycerol (TAG), phosphatidic acid (di-P PA), and diacylglycerol (DAG) in the liver

These LC neurons receive projections from pre-proglucagon expressing neurons, indicating a possible role in the physiologic control of food intake by the endogenous GLP-1 system

So were almost certainly capturing a skewed slice of the full picture. Neil Sehgal, ME, MS Second, we cant say anything about causality