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One study showed that injections of semaglutide (the active ingredient in Wegovy), which is administered for diabetes or weight loss in the skin of the abdomen, thigh or upper arm, produced little to no injectionsite pain

Some patients taper to a lower maintenance dose with their physician's guidance

As a representative GLP-1RA drug, liraglutide has been widely recognized as an effective treatment for obesity by suppressing appetite and promoting satiety [51]

Neurogenic inflammation (inflammation that affects the peripheral nervous system, a network of nerves that runs throughout the head, neck, and body) and neuroinflammation (inflammation that affects the brain and spinal cord) are involved in migraines with and without auras and chronic migraines, according to a study published in the journal FASEB BioAdvances