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And how does their staying power turn into effects like lower risk of stroke or improved osteoarthritis

In particular, they target areas that are important for homeostatic feeding, such as the hypothalamus, and for hedonic responses, such as the nucleus accumbens (NAc), ventral tegmental area (VTA), and laterodorsal tegmental area (LDTg) (Alhadeff et al., 2012

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Though more research is needed, scientists believe these drugs could open a powerful new front in addiction therapy