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Clinical trials with liraglutide showed not only a significant increase in satiety sensation, but also a notable reduction in the desire for sugar-, fat-, and salt-rich foods, accompanied by modifications in the hormonal profile, particularly in peptide YY (PYY) levels

Endocrinology (2017) 158(12):421832

Nakamura T, Ito T, Uchida M, Hijioka M, Igarashi H, Oono T, Kato M, Nakamura K, Suzuki K, Jensen RT, and Takayanagi R

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Reflux that doesn't improve after 68 weeks of lifestyle changes + medication
