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Many plans require a type 2 diabetes diagnosis or BMI above 30 with related conditions before approving these medications

Subsequently, Moore proposed the hypothesis that intestinal secretions might have a glycemic-lowering effect in diabetics, which was the first study to suggest an effect of intestinal secretions on blood glucose (Perley and Kipnis, 1967)

Manning Fox, Michael J

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GLP-1 is a naturally occurring incretin hormone produced by intestinal L-cells in response to food intake