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We subsequently proceeded to perform a sensitivity analysis using an E-value measurement to assess for potential unmeasured confounds that may influence the outcome of interest

Symptomatic management for mild injection site reactions includes: Applying a cool compress or ice pack wrapped in a thin cloth for 10 to 15 minutes to reduce swelling and discomfort Avoiding rubbing or massaging the injection site, which may increase irritation Using over-the-counter oral antihistamines (such as cetirizine or loratadine) for itching, if approved by a healthcare provider Applying fragrance-free, hypoallergenic moisturizer to dry or irritated skin around (not directly on) the injection site Patients should consult their healthcare provider before applying topical medications to injection sites, as these may mask signs of infection

Before switching, spend 2 to 3 weeks tracking calories meticulously, maintaining consistent exercise, and measuring body composition, not just weight

At 48 weeks, relative liver fat reductions reached -81.7% and -86.0% with 8mg and 12mg doses respectively

Patients can now obtain prescriptions after completing an online questionnaire or a brief virtual consultation, making the drugs far more accessible to people seeking to lose weight for cosmetic reasons