tirzepatide and cancer risk in Individuals with and without Diabetes: A Systematic Review and Meta-Analysis Tirzepatide—Friend or Foe in Diabetic
Description
Rapid weight loss may include muscle mass

Diabetic retinopathy complications: rapid improvement in glycemic control may worsen diabetic retinopathy acutely
Similarly, both acute and chronic treatment with ICV exendin-4 has been shown to reduce circulating plasma TG, cholesterol, and low-density lipoprotein cholesterol (LDLc) in addition to hepatic lipids

E., Magliano, D

However, it also turns out that interaction of GLP-1 agonists with receptors found on brain cells leads to feelings of satiety and reduced hunger