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Gastroenterologists are being increasingly consulted for the side effects, and a discussion around best management of these symptoms is presented

Trajectory of weight regain after cessation of GLP-1 receptor agonists: a systematic review and nonlinear meta-regression

found that GLP-1RA medications may have broader heart and metabolic effects, as well as reduce inflammation in addition to weight loss and glucose control in high-risk populations

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In this study, unlike previous studies using non-diabetic animals, we demonstrated using diabetic model rats and confocal laser scanning microscopy that the GLP-1/GLP-1R complex was located in the endosome of diabetic islets