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Biochem J 440(3):385395 [DOI] [PMC free article] [PubMed] [Google Scholar] Hassan NF et al (2024) The potential role of Tirzepatide as adjuvant therapy in countering colistin-induced nephro and neurotoxicity in rats via modulation of PI3K/p-Akt/GSK3-/NF-kB p65 hub, shielding against oxidative and endoplasmic reticulum stress, and activation of p-CREB/BDNF/TrkB cascade

While there is no consistently effective treatment to reverse NAION, timely assessment matters for diagnosis, for preventing risk to the fellow eye, and for coordination with your primary care provider or prescribing clinician

Limitations We recognise that the evidence may be limited due to the small sample sizes in the astronaut studies and some of the studies include astronauts with repeat spaceflight experience

People with this condition fall asleep at unwelcome times, including when driving or giving a presentation

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