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[1] [2] The pivotal SURPASS clinical trial programme, which evaluated tirzepatide's efficacy and safety in thousands of patients with type 2 diabetes, did not identify lymph node swelling as a recognised adverse effect

However, recent studies in rats have shown that overeating can lead to problems in the brains reward system that resemble those seen in drug addiction

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When tirzepatide has already delayed your gastric emptying by 30-50%, adding a meal that takes 4-6 hours to clear your stomach creates a recipe for severe nausea, bloating, and vomiting

Sometimes I make a bowl of oatmeal midday, and I struggle to eat it