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[DOI] [PMC free article] [PubMed] 16.Nrregaard PK, Deryabina MA, Tofteng Shelton P, Fog JU, Daugaard JR, Eriksson PO, et al

In healthy humans, dosing with 4.5 mg of tirzepatide resulted in significant reductions in fasting glucose vs placebo and improvements in glucose tolerance that were comparable to those of 1.5 mg dulaglutide

Species differences in renal development and associated developmental nephrotoxicity

We calculated this by taking the product of the weights calculated from the conditional probabilities of treatment discontinuation or switching, administrative censoring (end of study period/end of registration with practice), and death by using the covariates listed above

Up to 85% of participants on tirzepatide achieved an A1C of less than 7%