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These warrant a phone call to your prescriber: Vomiting more than 24 hours preventing fluid intake Severe abdominal pain that does not resolve in a few hours Diarrhoea lasting more than 3 days Constipation lasting more than 7 days despite fibre and fluids Persistent dizziness or near-fainting episodes Inability to eat or drink for more than 24 hours Signs of dehydration (dark urine, dry mouth, dizziness on standing) Any of the serious side effects listed above Frequently Asked Questions When do semaglutide side effects peak

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This translates to 1.5 million fewer CVD events over 10 years, with most preventable cases among men (2.2%) and white individuals (2.01%)

PMCID: PMC12922244

Metformin and GLP-1 medications are frequently prescribed together for patients who have both type 2 diabetes and obesity