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Methods Based on a systematic literature review (SLR) and Bayesian network meta-analysis (NMA), the efficacy and safety of semaglutide 2.4 mg, liraglutide 3 mg and tirzepatide 5, 10 and 15 mg were compared in adults without type 2 diabetes, and with either obesity (body mass index [BMI]30 kg/m2) or overweight (BMI27 kg/m2) with 1 obesity-related complication

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Gastrointestinal (GI) side effects are common in people with diabetes treated both with metformin and with GLP-1 receptor agonists (GLP-1RAs), and they

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(However, it is ONLY licensed for Obesity and NOT for Type 2 Diabetes) 6

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Sue Decotiis warn of potential risks.

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Patients on GLP-1 injections can lose 15 to 20 percent of their body weight over 12 to 18 months

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