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In part, these medications work by sending signals to the brain to decrease appetite and by slowing digestion, which helps people feel fuller for longer

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12 In a mouse model of RA, inhibiting DPP4 was found to enhance the entry of synovial fibroblasts into cartilage cells

Stimulation of Gut Motility: Fiber can stimulate peristalsis, the wave-like contractions of the intestines that propel food and waste through the digestive system

For rheumatoid arthritis, the American College of Rheumatology recommends disease-modifying antirheumatic drugs (DMARDs) as first-line therapy, with methotrexate being the most commonly prescribed conventional synthetic DMARD
