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Key kidney markers: eGFR below 60 ml/min indicates moderate kidney function loss

Hence, understanding these mechanisms is essential for developing targeted dietary interventions to enhance glycaemic regulation and overall metabolic health in individuals with T2D

The standard titration approach The clinical trials used specific escalation protocols designed to minimize GI disturbance while still reaching therapeutic dose levels

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Transcriptional Programs Upon activation by SLU-PP-332, ERRs bind to ERR response elements (ERREs) in the promoters and enhancers of target genes, recruiting transcriptional coactivators and promoting gene expression