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Dose splitting addresses both problems simultaneously: lower peaks reduce side effects, and higher troughs maintain appetite suppression throughout the week
Diabetes Care 2021
Garcia Luna, C
[DOI] [PubMed] [Google Scholar] [27].Zhu DD, Zhang XP, Zhang BL, Hao YY, Guo XD, Safety Assessment of Microneedle Technology for Transdermal Drug Delivery: A Review, Advanced Therapeutics 3(8) (2020) 2000033
However, adverse events, particularly nausea and digestive symptoms, were more common among participants taking GLP-1 drugs, and some stopped treatment due to side effects
