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Animal studies : In studies where tirzepatide was given to pregnant animals, some harmful effects were seen in the fetuses

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Supplementation with Gymnema sylvestre reduced excessive eating, fatigue, blood glucose (fasting and post-prandial), and glycated hemoglobin and there was a favourable shift in lipid profiles and in other clinical-biochemical tests

The marked improvements in papilledema and visual outcomes suggest that early intervention with tirzepatide could potentially alter the natural history of IIH, especially in cases refractory to conventional therapies