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PBH is thought to be caused by an excessive glucagon-like peptide-1 (GLP-1) response leading to hypoglycemia and impaired quality of life

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Plasma DPP-4 activity and TG excursion after olive oil administration was reduced, and plasma active GLP-1 was increased to a greater extent after administration of systemically active versus gut-selective doses of sitagliptin in Dpp4 Gut+/+ mice (Figure 4, A and B)

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