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Description
Glucagon-like peptide 1 (GLP1) analogues are licensed options for obesity, but new treatments are required to obtain better weight loss and to directly address other co-morbidities, such as non-alcoholic fatty liver disease

Learn causes, red flags, tests, and when to seek care.

Here authors report the peptide-free crystal structure of human GLP-1R in an inactive state which reveals a unique closed conformation of the extracellular domain.

In New England Journal of Medicine (NEJM) Wharton S, et al.N Engl J Med

Lancet Gastroenterol Hepatol
