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The rapid divergence observed in mortality, MACE, and MAKE almost immediately after the start of follow-up prompted us to explore alternative mechanisms beyond general metabolic improvements

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All these factors indicate that you possibly just need time or dose adjustment and likely should continue. However, if you have no reduction in appetite after eight to 12 weeks, no weight loss or blood sugar improvement after three to six months or persistent severe side effects that prevent you from going up in dosage, GLP-1s may not be for you, adds Dr

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These financial realities are actively shaping coverage decisions