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While the drugs have been dubbed a miracle amid rising obesity, they are expensive, running upward of $1,000 a month, though some discounts are available for those who buy directly from the companies that bring monthly costs down considerably

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In a 2024 review of three peptides, the FDA noted side effects like increased heart rate, chest tightening, headache, nausea, diarrhea, and elevated liver enzymes, as well as skin irritation and pain at the injection site

The trials missed their primary endpoint

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