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PWD are even more susceptible because combining any one of these variables with even slightly high blood sugar levels creates an easy environment for the overgrowth of yeast
Neurons are highly vulnerable to DNA damage caused by ROS from mitochondrial metabolism, while upstream defects in RNA processing involving defects in splicing, transport, and stress granule dynamics can disrupt protein homeostasis and promote aggregation
6:105-113 [PubMed: 29221659] 357
