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Rubio, G
Gut 63, 15131521

Contraindications: - Personal or family history of medullary thyroid carcinoma (MTC) - Multiple Endocrine Neoplasia syndrome type 2 (MEN2) - Serious hypersensitivity to orforglipron Safety profile: Common adverse effects include nausea, diarrhea, constipation, vomiting, abdominal pain, and fatigue

however, it led to a significant decrease in fat mass, consistent with lower plasma leptin levels (Fig

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