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However, when testing for an interaction between the GLP1R variant (rs10305420) and the GIPR variant (rs1800437), we identified weak evidence for interaction ( P = 0.018
Genome Biol 9, R81, doi: 10.1186/gb-2008-9-5-r81 (2008)

Consider microdosing: Splitting the weekly dose into smaller, more frequent injections reduces peak plasma concentrations and typically reduces side effects
Enhanced Mobility : Improves joint function and flexibility

Orlistat can impair absorption of fat-soluble vitamins (A, D, E, K), so supplementation is recommended
