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Now, for the first time, it is becoming genuinely cheap in a hugely populous country where all three conditions are widespread and rising

The FDA has not reviewed or approved concurrent use of these agents, and compounding pharmacies operate within state regulations that require clinical oversight

Another factor in the process is certainty

Eligibility requires a BMI over 35 with at least one weight-related condition, or sometimes a BMI over 30 if other criteria are met

What the Clinical Data Shows Clinical trials include both men and women, and results are generally reported as combined averages: STEP 1 trial (semaglutide 2.4mg): 14.9% average body weight loss over 68 weeks