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For context, that puts the tablet broadly in the territory of the 2.4 mg weekly injection studied in STEP 1 (Wilding et al., 2021), which is the comparison most patients will reach for

Sometimes it simply comes down to a tradeoff between a gastric bypass with a lower risk of post-op GERD, or gastric sleeve with a higher risk of GERD but a much lower overall long-term risk.

Less common but important risks include dehydration from severe vomiting or diarrhoea, gallbladder problems, pancreatitis, and worsening of diabetic eye disease in some patients with diabetes

Its also approved to lower the risk of kidney failure or serious heart problems in people who have type 2 diabetes and kidney or heart disease

Exercise contributes to this as well