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with a BMI of 30 or more and heart failure with preserved ejection fraction, uncontrolled hypertension, or chronic kidney disease stage 3a or above

Elecoglipron is an oral small molecule GLP-1 RA (receptor agonist), Vanita Aroda, MD, director of Diabetes Clinical Research at Brigham and Womens Hospital, associate professor of medicine at Harvard Medical School, and lead author of this study, told Medical News Today

These results indicate that NaB is able to prevent the progression of NAFL to NASH via promoting hepatic GLP-1R expression

Sitaglipitin was the first DPP-4 to be approved by the FDA with the most aftermarket studies

In terms of study subjects, the focus was on patients with T2DM, T2DM patients complicated with cardiovascular diseases, or animal models of diabetes-related heart diseases