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Am J Hypertens 27(1):130139 Kim M, Platt MJ, Shibasaki T, Quaggin SE, Backx PH, Seino S, Simpson JA, Drucker DJ (2013) GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure

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Cavero-Redondo I, Martinez-Vizcaino V, Fernandez-Rodriguez R, Saz-Lara A, Pascual-Morena C, lvarez-Bueno C

Potential Side Effects Linked to Receptor Activity The most common side effects in phase 2 trials were gastrointestinal, including nausea, vomiting, and diarrhoea, consistent with GLP-1R agonist class effects