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Susan Spratt, an endocrinologist and the senior medical director for the Population Health Management Office at Duke Health in North Carolina, said a monthly GLP-1 drug could be good for patients who struggle with sticking to the dosing schedule or who just prefer taking medication less often

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In follow-up from the STEP 1 trial on semaglutide, average weight loss on semaglutide was 17.3% at week 68

Histological analysis revealed that mice treated with HORN-MN exhibited increased UCP1 protein expression in iWAT, along with reduced adipocyte size, indicating successful browning of white adipocytes