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Injectable semaglutide produced an average 14.9% body weight reduction over 68 weeks in the STEP 1 trial
doi: 10.1007/s00125-019-04997-5 137 Lloyd-JonesDMAllenNBAndersonCAMBlackTBrewerLCForakerREet al
The next couple pathways we will sorta combine together as they are both metabolism coded, the PI3K/AkT/mTOR and AMPK pathways
A clinical study showed that semaglutide (2.4 mg once weekly) reduced body weight by 10-15% of initial weight compared to 2-3% with placebo
