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These converging findings indicate that sirtuins are key regulators of neuronal and mitochondrial homeostasis in PD as their impaired activity elevate oxidative stress, ATP depletion, S accumulation, and dopaminergic neuronal loss (Xu et al., 2023)

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doi: 10.1210/clinem/dgaa891 50 AlanteetAAAttiaHAShaheenSAlfayezMAlshanawaniB
REPORT OF FOUR CASES

(2025, July 1)