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Figure 12: Photograph Professor Vincent Marks (1930-2023), credit: Seaton)

In addition, G protein-coupled excitatory GLP-1 receptors are located in central regions subserving disparate brain functions (eg, ventral tegmental area, nucleus accumbens, hippocampus, lateral septum, hypothalamus)

Others argue the safety is compromised

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Neuroprotective role of GLP-1 analog for retinal ganglion cells via PINK1/Parkin-Mediated mitophagy in diabetic retinopathy