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The key consideration with semaglutide specifically is the gastrointestinal side effect profile
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If other health problems such as prediabetes or polycystic ovary syndrome (PCOS) are present, GLP-1RA therapy might be preferred over other treatment options
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Evidence suggests that GLP-1 receptor agonists can effectively reduce visceral adipose tissue, though the degree to which this reduction is preferential compared to subcutaneous fat continues to be investigated
