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Description
Endogenous GLP-1 has a half-life of 2 minutes, as dipeptidyl peptidase enzymes rapidly inactivate incretin hormones
Diabetes and Alzheimers Disease Diabetes is closely linked to AD, and a meta-analysis showed that patients with diabetes had a significantly higher incidence of AD than in those without diabetes (relative risk [RR], 1.53
After a few years of injectable dominance, oral formulations are emerging as a game-changer for adherence and ease of use thanks to their lack of cold-chain requirement, but also a game-changer for their ability to unlock the long-term maintenance opportunity [14]
In summary, exenatide was a trailblazer
Molecular Mechanisms of Neuropathological Changes in Alzheimers Disease: A Review
