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NAION is believed to occur in this setting from a rapid reduction in perfusion, such as with glucose reduction or weight loss (reducing plasma volume), coupled with GLP-1 influence upon the vascular tone leading to vasodilatation, ultimately resulting in hypoperfusion [36]

Some GLP-1RAs have been approved in pediatric population several years ago

GLP-1 receptor agonists such as semaglutide (Ozempic), tirzepatide (Mounjaro, Zepbound), and liraglutide (Victoza) are advanced medical versions of a hormone your gut produces

The fatty acid conjugation is essential for the once-weekly dosing that makes retatrutide dosing schedules practical

Cravings, particularly for high-fat or high-sugar foods, often diminish