where do glp 1 drugs come from The GLP-1 revolution: What UAB researchers are discovering about how these work GLP-1 Drugs & What They

Prior reports have also cited cost to be a barrier to use for a large portion of patients, with monthly costs up to $1349 before insurance, rebates, or other discounts ( 2 , 12 )

Tirzepatide 15 mg was also associated with higher incidence of vomiting (OR 5.50 [95% CI 2.40, 12.59], I 2 0%) and diarrhoea (OR 3.31 [95% CI 1.40, 7.85], I 2 52%), while more participants receiving tirzepatide 10 mg experienced vomiting (OR 2.98 [95% CI 1.13, 7.80], I 2 0%) (Table 2)

Pharmacological management of obesity: aneEndocrine society clinical practice guideline

These changes increase the risk of gastroparesis and bowel blockage [12]

But, theres a lack of research involving human subjects on this matter