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Liraglutide, semaglutide and dulaglutide have demonstrated cardiovascular benefits, and Wegovy recently added to this evidence base: in the SELECT trial, patients on Wegovy had a 20% lower incidence of heart attack, stroke or death from heart disease compared to those on a placebo

It is also a substrate for sirtuins, a family of NAD+-dependent deacetylases that regulate metabolism, inflammation, and aging

Metformin (in a dose, biological sample, and species-specific manner) treatment has the potential to activate targets resulting in an overall improvement of fertility

After factoring in GLP-1 prescriptions and comparing women of similar ages, races and ethnicities, BMIs, breast densities and Type 2 diabetes statuses, researchers found significantly lower rates of breast cancer in those who had used a weight-loss medication
