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SGLT-2 inhibitors were associated with lower risk of renal outcome as compared with placebo (36% lower risk), DPP-4 inhibitors (40% lower risk) and GLP-1RA (22% lower risk)

The beneficial effects of SGLT2 inhibitors on metabolic outcomes (BP control, body weight) were also shown in a meta-analysis of RCTs in non-diabetic individuals [96]

[DOI] [PubMed] [Google Scholar] 11.le Roux CW, Aylwin SJB, Batterham RL, Borg CM, Coyle F, Prasad V, et al

Epub 2017 Feb 1
doi: 10.1021/acs.molpharmaceut.5b00278 [DOI] [PubMed] [Google Scholar] 154.Kapitza C, Zdravkovic M, Hindsberger C, Flint A
