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References: (1) Gentinetta, S., et al
The increasing prevalence of obesity worldwide and its associated pressure on healthcare systems, along with the reputation of GLP-1 drugs for inducing significant weight loss (approximately 1525+%, significantly higher than previous generations of obesity drugs), are driving GLP-1 drug expansion into new markets like China
Dysregulation of MMP-2, 8, and 9 in HS: from localized matrix remodeling to systemic inflammatory and metabolic perturbations Key players of inflammation, tissue remodelling and fibrosis in HS pathogenesis are MMPs
