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While these findings are observational and require confirmation in prospective studies, they highlight the potential of GLP-1 therapies to influence long-term musculoskeletal and inflammatory outcomes in patients with diabetes. For more information: Betul Ibis, MD, can be reached at [email protected].

Previously, for those with diabetes, hypertension and a low risk of atherosclerotic CV disease (10-year risk less than 15%), a blood pressure target of less than 140/90 mmHg was the recommendation

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And this makes sense the FDA wants to incentivize products going through the rigorous approval process to ensure safety and efficacy

Due to DPP-4 and renal clearance, native GLP-1 in humans has a half-life of about 1-2 minutes (21, 22, 89)