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Description
Less nausea and vomiting Nausea is a common side effect of GLP-1s, affecting around 10-25% of participants in clinical trials

Metformin Many hypothyroid patients also have insulin resistance or type 2 diabetes and take metformin alongside tirzepatide

Biology of Incretins: GLP1 and GIP. Gastroenterology

These medications also dampen the brains reward to sugary foods and other cravings

After reviewing data submitted to the FDAs Adverse Event Reporting System between 2018 and 2024, McCall and his coauthors found that compounded GLP-1 medicines were correlated with a greater likelihood of abdominal pain, nausea, diarrhea, gallbladder inflammation, and suicidality compared to standard formulations, as well as more frequent hospitalization for those adverse effects
