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The once-a-day pill, from the makers of the Wegovy weight-loss jab, can now be bought privately in UK pharmacies.

A new randomized clinical trial just published inJAMA Psychiatrytested semaglutide (a GLP-1 agonist) in people with schizophrenia, prediabetes, and obesity who were taking antipsychotics

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Several ongoing clinical trials are now evaluating: Biological aging biomarkers Physical function and frailty Vascular aging Cognitive outcomes Epigenetic aging Long-term healthspan endpoints As longevity physicians, we should remain enthusiasticbut scientifically disciplined

Includes what to expect and when to speak to a clinician.