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Through improved glycemic control and promoting sustained weight loss, GLP-1 RAs enhance insulin sensitivity in adipose tissue and muscle, accompanied by reductions in pro-inflammatory cytokines (TNF, IL-1, IL-6) and elevations in adiponectin

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Em entrevista coluna, o farmacutico e bioqumico Alexandre Zambrotta explica que a principal diferena da nova substncia para outras drogas desenvolvidas com o mesmo objetivo est em sua ligao ao glucagon, hormnio formado por 29 aminocidos que atua como contrarregulador da insulina
