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At microdose levels, this risk is likely minimal, but patients with existing gallbladder disease should be monitored

They do this by mimicking glucagon-like peptide-1 (GLP-1), a hormone made naturally in the human gut

For participants receiving 40 mg daily of oral semaglutide, three different dose-titration protocols were used where patients were titrated up to the full 40 mg dose in 6 weeks (fast dose escalation), 12 weeks (standard dose escalation), or 24 weeks (slow dose escalation)

Incretin analogs, a class of neurohormones that act in a multimodal way, represent some of the most advanced options in anti-obesity pharmacotherapy

Diabetes itself was not an independent risk factor for any of the complications