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doi: 10.1146/annurev.ph.34.030172.000305

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Approved for type 2 diabetes, Ozempic gained massive off-label use in obesity, supported by real-world weight loss outcomes

The introduction of oral GLP-1 receptor agonists has offered patients a convenient way to effectively manage their weight and adhere to the medication regimen

Combination of PIO with GLP-1R agonists The possible role of exenatide (EXE) and PIO combination therapy on hepatic fat content was investigated in 21 patients with T2D being on diet ( n = 4) and/or MET therapy for at least 3 months ( n = 17) [124]
